Reasons:

1. Wrong starting point is set in software

Solution:

select current position as starting point in softwares.

RDWorks:

Locate on the bottom left corner, the option of "Position" please select to Current position.

Lightburn:

Locate on the bottom left corner, the option of " Start from", please select to current position. 

2. Origin setting is not proper on LCD panel

Solution:

Open origin setting windows: Z/U or Menu button>>origin set+.

Make sure the "Multiple Origins Enable" is not selected, like below.

End.